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Acquisition of H1975 and HCC827 cells resistant to AZD9291. The drug sensitivity of (a) H1975 (
) and H1975/AZDR (
) and (b) HCC827 (
) and HCC827/AZDR (
) cells was detected by methyl thiazolyl tetrazolium (MTT) assay. The viability and proliferation of (c) H1975 (
) and H1975/AZDR (
) and (d) HCC827 (
) and HCC827/AZDR (
) cells was detected by MTT assay. IC50, half maximal inhibitory concentration.
