Table 1.
Characteristics of patients stratified by SLX staining
| Moderate | Low | P | ||
|---|---|---|---|---|
| Characteristics | High | (n = 108) | (n = 48) | (n = 89) |
| Gender (male/female) | 51/57 | 21/27 | 50/39 | 0.295 |
| Age (years) | 67 (39–85) | 69 (27–93) | 68 (20–86) | 0.394 |
| Smoking (never/ever) | 47/61 | 29/19 | 40/49 | 0.126 |
| p‐stage (UICC8) | ||||
| IA1/IA2/IA3/IB | 13/33/32/30 | 6/13/15/14 | 5/30/21/33 | 0.480 |
| Grade (G1/G2, G3) | 39/69 | 23/25 | 33/56 | 0.352 |
| Invasion/tumor ratio | ||||
| ≤ 50%/> 50% | 16/92 | 6/42 | 8/81 | 0.452 |
| Lymphatic/vascular invasion never/ever | 70/38 | 31/17 | 67/22 | 0.225 |
| Predominant histologic subtype† | ||||
| Lepidic | 15 (1) | 6 (0) | 8 (0) | 0.059 |
| Acinar | 6 (3) | 1 (0) | 10 (4) | |
| Papillary | 74 (22) | 31 (6) | 44 (11) | |
| Mucinous | 4 (1) | 4 (2) | 13 (5) | |
| Micropapillary | 3 (2) | 2 (2) | 5 (3) | |
| Solid | 5 (3) | 4 (2) | 9 (4) | |
| STAS (absent/present) | 76/32 | 36/12 | 62/27 | 0.786 |
| Serum SLX (U/ml) | 23.0 (10.0–85.4) | 19.7 (10.6–51.7) | 21.1 (11.5–48.6) | 0.330 |
| Serum CEA (ng/ml) | 3.6 (0.7–65.8) | 3.4 (0.5–80.5) | 3.0 (0.6–122) | 0.943 |
†
Number of patients with spread through alveolar spaces (STAS) is shown in parentheses. Values are shown as N or median (range), except for the predominant histologic subtype category of the table.
UICC8, Union for International Cancer Control, 8th Edition.