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. 2019 Feb 27;10(4):848–855. doi: 10.1111/1759-7714.13013

Figure 4.

Figure 4

Inhibition of the Wnt/β‐catenin pathway suppresses IL‐6/STAT3 and EGFR/PI3K/AKT signaling pathways. (a) The effects of XAV939 on the expression of proteins involved in the IL‐6/STAT3 and PI3K/AKT signaling pathways. Western blotting revealed the effects of (b) PI3K inhibitor ZSTK474 and (c) STAT3 inhibitor Niclosamide (Nicl) on β‐catenin level. Actin was used as an internal loading control.