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. 2019 Feb 21;10(4):839–847. doi: 10.1111/1759-7714.13011

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© 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Mutation spectrum of large cell carcinoma (LCC), large cell neuroendocrine carcinoma (LCNEC), and small cell lung cancer (SCLC). (a) Mutation profiles of each subtype. Smoking history and pathological subtype are denoted on top of the oncoprint. Each column represents a patient and each row represents a gene. The color gradient represents allelic fraction. (b) Bar graph summarizes the mutation frequency of the most frequently mutated genes in this cohort. , LCC; , LCNEC; , SCLC.

Inline graphic — Mutation spectrum of large cell carcinoma (LCC), large cell neuroendocrine carcinoma (LCNEC), and small cell lung cancer (SCLC). (a) Mutation profiles of each subtype. Smoking history and pathological subtype are denoted on top of the oncoprint. Each column represents a patient and each row represents a gene. The color gradient represents allelic fraction. (b) Bar graph summarizes the mutation frequency of the most frequently mutated genes in this cohort. , LCC; , LCNEC; , SCLC.