Table 1.
Quantity of each bacterial toxin and bile acid that can be removed by the recommended single dose of Enterosgel and Charcodote (Enterosgel 3 doses daily, Charcodote every 4–6 hours).
| Sorbent | Enterosgel (single dose 22.5 g) | Charcodote (single dose 25–50 g) |
|---|---|---|
| C. difficile TcdA (ng) | 739.1 | 2819–5638 |
| C. difficile TcdB (µg) | 764.0 | 1073–2146 |
| Shiga toxin Stx2-B (µg) | 151.0 | 3375–6750 |
| Endotoxin (mg) | 3.7 | 39.1–78.2 |
| Taurocholic acid (mg) | 13.5 (1.3%) | 172.3 (17.2%) |
| Glycocholic acid (mg) | 38.2 (3.8%) | 349.6 (34.9%) |
| Taurochenodeoxycholic acid (mg) | 32.3(3.2%) | 390.9 (39.0%) |
| Glycochenodeoxycholic acid (mg) | 104.9 (10.5%) | 404.6 (40.5%) |
In brackets the daily percentage removal of each bile acid (calculated using 2%w/v bile salt concentration, average 600 mL bile/day, approximate equal concentrations of each bile acid).