Table 1.
PLB | SERCA | PLB/SERCA | PKP | Plako | ZASP | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
β | p | β | p | β | p | β | p | β | p | β | P | |
Age | 0.07 | 0.36 | −0.1 | 0.34 | 0.04 | 0.66 | −0 | 0.97 | 0.1 | 0.41 | 0.1 | 0.48 |
EF | 0.05 | 0.52 | −0.1 | 0.12 | −0 | 0.87 | −0 | 0.93 | −0.1 | 0.39 | −0 | 0.75 |
Statins | −0 | 0.8 | 0.05 | 0.52 | 0.11 | 0.28 | 0 | 1 | 0.08 | 0.541 | −0.2 | 0.18 |
CCS | −0.1 | 0.46 | 0.02 | 0.84 | −0.1 | 0.21 | −0.2 | 0.2 | 0.05 | 0.705 | 0.23 | 0.12 |
ASS | −0.2 | 0.04 | 0.03 | 0.74 | 0.11 | 0.34 | 0.05 | 0.81 | −0.4 | 0.002 | 0.01 | 0.95 |
ACE or AT1 | 0.1 | 0.25 | −0 | 0.9 | −0 | 0.72 | 0.04 | 0.83 | 0.3 | 0.017 | −0.1 | 0.4 |
PLB | 0.78 | 0 | 0.79 | 0 | 0.04 | 0.91 | −0.3 | 0.209 | −0.2 | 0.54 | ||
SERCA | 0.81 | 0 | −0.9 | 0 | −0.1 | 0.7 | −0.1 | 0.728 | 0.17 | 0.52 | ||
PLB/SERCA | 0.51 | 0 | −0.6 | 0 | −0.3 | 0.29 | −0 | 0.954 | 0.04 | 0.84 | ||
PKP | 0.01 | 0.91 | −0 | 0.7 | −0.1 | 0.29 | 0.01 | 0.962 | 0.14 | 0.29 | ||
Plako | −0.1 | 0.21 | −0 | 0.73 | −0 | 0.95 | 0.01 | 0.96 | 0.34 | 0.04 | ||
ZASP | −0.1 | 0.54 | 0.06 | 0.52 | 0.02 | 0.84 | 0.2 | 0.29 | 0.28 | 0.043 |
Protein expression data were normalized to CSQ expression.
β, standardized regression coefficient; ACE, Angiotensin-converting enzyme antagonist; ASS, acetylsalicylic acid; AT1, angiotensin receptor type 1 antagonist; CCS, Canadian Cardiovascular Society angina class; EF, ejection fraction; PKP, plakophilin; Plako, plakoglobin; PLB, phospholamban; SERCA, sarcoplasmic reticulum Ca2+-ATPase; ZASP, Cypher/ZASP.