Table 1.
Baseline characteristics of healthy controls and patients of acromegaly.
| Parameters | Group HC Healthy controls (n = 10) MEAN ± S.D. (Mean Rank) |
Group A Acromegaly without Diabetes (n = 10) MEAN ± S.D. (Mean Rank) |
Group B Acromegaly with Diabetes (n = 10) MEAN ± S.D. (Mean Rank) |
Non parametric tests (Man Whitney/Kruskal Wallis) Chi square (p value) Post Hoc |
|---|---|---|---|---|
| Age (yrs) | 29.7 ± 4.8 (12.10) |
32.4 ± 10.5 (14.85) |
36.8 ± 7.6 (19.55) |
3.68 (p = 1.59) |
| Sex (n) M:F | 5:5 | 5:5 | 5:5 | 0.0005 (p = 1.00) (Pearson Chi-square) |
| BMI (Kg/m2) | 27.7 ± 2.4 (18.95) |
26.5 ± 2.7 (13.10) |
27.1 ± 3.9 (14.45) |
2.69(0.260) |
| HbA1c (%) | 5.0 ± 0.35 (07.15) |
5.4 ± 0.24 (13.85) |
9.6 ± 3.5 (25.50) |
22.385 (0.0005***) HC < B***, A < B** |
| GH (basal) (ng/ml) | 0.07 ± 0.07 (05.50) |
74.8 ± 78.1 (20.30) |
65.8 ± 56.9 (20.70) |
19.52 (0.0005***) HC < A***, HC < B*** |
| IGF 1 (ng/ml) | — | 1198.9 ± 349.4 (12.50) |
972.5 ± 319.8 (08.50) |
30 (0.131) |
| Tumor volume (cu mm) |
— | 5132.4 ± 6288.7 (9.30) |
7115.0 ± 8504.2 (11.70) |
38 (0.364) |
*P < 0.05, **P < 0.01, ***P < 0.001.