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. 2019 Apr 5;39(4):BSR20182259. doi: 10.1042/BSR20182259

Figure 3. Electron micrographs showing reduction in the size and shape of AT polymers by sorbitol and trehalose.

Figure 3

AT Polymers were formed by heating 10 µM of the protein at 60°C for 90 min. Samples were stained negatively with 1.5% (w/v) uranyl acetate, and viewed with a magnification of up to ×50000. AT incubated at (A) 0 min, (D) 90 min; AT incubated in the presence of 1.5 M sorbitol at (B) 0 min and (E) 90 min and in the presence of 1 M trehalose at (C) 0 min and (F) 90 min. Insets in D–F shows enlarged view of polymers.