Table 1.
Strains used in the studies
| Strain | Source | Resistance summary | Lefamulin MIC (mg/L) |
|---|---|---|---|
| S. pneumoniae | |||
| 248092 | IHMA | MDR | 0.06–0.12 |
| 411627 | IHMA | MDR | 0.03–0.06 |
| 49619 | ATCC | PSSP | 0.03–0.06 |
| B1378 | BAL, SENTRY 2010 | PISP | 0.12 |
| B1382 | BAL, SENTRY 2010 | PSSP | 0.25 |
| B1383 | BAL, SENTRY 2010 | PRSP, MR | 0.25 |
| B1385 | BAL, SENTRY 2010 | PSSP | 0.5 |
| B1386 | BAL, SENTRY 2010 | PISP, MR | 0.5 |
| S. aureus | |||
| 29213 | ATCC | MSSA, quality control strain | 0.12 |
| B154 | ATCC 25923 | MSSA | 0.12 |
| B341 | ATCC 33591 | MRSA | 0.06–0.12 |
| B1118 | SENTRY 2002 | MRSA | 0.12 |
| B1325 | SENTRY 2010 | MRSA | 0.5 |
| B1331 | SENTRY 2010 | MRSA | 0.5 |
IHMA, International Health Management Associates; MR, macrolide resistant; PISP, penicillin-intermediate S. pneumoniae; PRSP, penicillin-resistant S. pneumoniae; PSSP, penicillin-susceptible S. pneumoniae.