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. 2019 Apr 3;4(2):e00040-19. doi: 10.1128/mSphere.00040-19

TABLEĀ 2.

Types of ICEs identified in the strains

Element Strain(s) Integration site Integrase(s)a (n) Size (nt)b ICE TPA
GenBank
accession no.
ICEEaI(1) 3375 Siroheme synthase and HP Tyr (1) 63,549 BK010586
ICEEaI(1) CSID3015183678 Inside mutY Tyr (1) 62,894 BK010587
ICEEaI(1) FDAARGOS-198 EngB and ElaA Tyr (1) 62,860 BK010588
ICEEaI(1) NUHP1 SlyD and HP Tyr (1) 62,960 BK010589
ICEEaI(2) FDAARGOS-198 TonB receptor and HP Tyr (3) 69,029 BK010590
ICEEaI(3) 37-75 Inside Ahp Tyr (1) 65,419 Not availablec
ICEEaI(4) CSID3000516074 HP and LuxR TF Tyr (1), DDE(1) 97,160 BK010591
ICEEaI(5) NCTC10588 Macrolide-efflux protein and LytR/AlgR TR Tyr (1) 81,809 Not availablec
ICEEaI(6) PW2806, PW2809 Efflux protein and peptidase Tyr (1) 79,842 BK010592
ICEEaI(7) NUH6 TomB receptor and HP Tyr (1) 59,635 BK010593
ICEEaI(8) NUH11 tRNA-Asp-GTCa Tyr (2) 95,803 BK010594
ICEEaII(1) 0422 tRNA-Leu-CAA No Int 63,840 BK010595
ICEEaII(1) CIP60.58 tRNA-Leu-CAA No Int 63,840 BK010596
ICEEaII(2) 502 tRNA-Leu-CAA IS481 (2) 38,146 BK010597
ICEEaII(3) 12012-2 PRCM tRNA-Leu-CAA No Int >56,734 BK010598
ICEEaII(4) AmMS250 tRNA-Leu-CAA No Int >64,773 Not availablec
ICEEaII(5) CIP111046 tRNA-Leu-CAA No Int 87,438 BK010599
ICEEaII(6) F3201 tRNA-Leu-CAA No Int 91,608 BK010600
ICEEaII(7) F3543 tRNA-Leu-CAA No Int 104,603 BK010601
ICEEaII(8) FMS-007 tRNA-Leu-CAA DDE (1) 73,167 BK010602
ICEEaII(9) NCTC10588 tRNA-Leu-CAA Ser (2) 67,087 Not availablec
ICEEaII(10) JM-87 tRNA-Leu-CAA Ser (1), IS481 (1) 36,967 BK010603
ICEEaII(11) NUH11 tRNA-Leu-CAA No Int 94,112 BK010604
ICEEaII(12) NUHP1 tRNA-Ser-GGA Tyr (1) 71,591 BK010605
ICEEaIII(1) R26, Ag1, Ar4-6, AR6-8 tRNA-Ser-TGA Tyr (4), DDE (1) 101,692 BK010606
ICEEaIII(2) R26, Ag1, Ar4-6, AR6-8 tRNA-Arg-ACG Tyr (1), DDE (1) 77,358 BK010607
ICEEaIII(3) As1 tRNA-Arg-ACG Tyr (1), Ser (1), DDE (1) >44,888 BK010608
ICEEaIII(4) As1 tRNA-Ser-TGA DDE (1) >31,354 BK010609
ICEEaIII(5) NUHP1 tRNA-Glu-TTC Tyr (4) 60,900 BK010610
ICEEaIII(6) NUHP1 tRNA-Glu-TTC Tyr (1) 74,499 BK010611
ICEEaIII(7) NUHP1 tRNA-Asp-GTC Tyr (1) 116,331 BK010625
ICEEaIII(8) NUHP1 tRNA-Asp-GTC Tyr (3) 109,040 BK010626
ICEEaIII(9) NUH6 tRNA-Gln-TTG Tyr (1) >30,166 BK010612
ICEEaIII(10) NUH6 tRNA-Glu-TTC Tyr (1) >33,929 BK010623
ICEEaIII(11) NUH6 tRNA-Asp-GTC Tyr (1) >98,049 BK010613
ICEEaIII(12) NUH11 Beta-lactamased Tyr (2)d 84,534 BK010614
ICEEaIII(13) 0422 tRNA-Gln-TTG Tyr (2), DDE (4) 67,662 BK010615
ICEEaIII(13) CIP60.58 tRNA-Gln-TTG Tyr (2), DDE (4) 66,636 BK010616
ICEEaIII(14) Po0527107 tRNA-Glu-TTC Tyr (1) >31,721 BK010617
ICEEaIII(14) V0378064 tRNA-Glu-TTC Tyr (1) >37,189 BK010618
ICEEaIII(15) JM-87 tRNA-Ser-TGA Tyr (1) 73,828 BK010624
ICEEaIII(16) 12012-2 PRCM tRNA-Glu-TTC Tyr (1) >31,732 BK010619
ICEEaIII(17) LDVH-AR107 tRNA-Asp-GTC Tyr (2) >84,845 BK010620
ICEEaIII(18) EM361-97 tRNA-Arg-ACG Tyr (1), DDE (2) 69,393 BK010621
ICEEaIII(19) EM361-97 tRNA-Glu-TTC DDE (1) >28,887 BK010622
a

Tyr, tyrosine type; Ser, serine type; DDE, DDE transposase; IS481, IS481 family of transposases; Int, integrase.

b

Size (in nucleotides [nt]) is shown. >, elements were partially assembled.

c

There are no assemblies in the NCBI database for these four strains, so we did not submit third party annotation (TPA) for these genomes to GenBank.

d

Two elements, ICEEaI(8) and ICEEaIII(12) in strain NUH11 combined and integrated between tRNA-Asp-GTC and beta-lactamase. These two elements may share the same integrase.