FIG 2.
Palatal tissue damage over time in rats inoculated with C. albicans and/or C. glabrata. Rats fitted with dentures were inoculated 3 times at 3-day intervals with 1 × 109 CFU C. albicans, C. glabrata, or both species together (5 × 108 CFU each). Swab samples of the palate over the removable denture portion were collected weekly for a period of 4 weeks postinoculation. Swab suspension fluid was tested for LDH levels. Figure represents cumulative data from 2 independent experiments with 2 to 5 rats per group. Data were longitudinally analyzed by repeated measures ANOVA (significance indicated on graph legend) and comparatively analyzed by one-way ANOVA (individual time points between groups) followed by the unpaired Student's t test at specific time points. **, P < 0.01.