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Effect of apical application for 16 h of different B. subtilis strains on IL-8 release of Caco-2 cells with or without subsequent 6 h basolateral stimulation with (A) IL-1β (20 ng/ml) or (B) flagellin (1 μg/ml), or (C) apical stimulation with DON (10 μM). EGCG was used as positive control. Labeled means without a common letter differ within each condition, p < 0.05.
