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. 2019 Mar 29;13:123. doi: 10.3389/fncel.2019.00123

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Copyright © 2019 Deng, Wang, Hu, Feng, Shao, Xie, Wu, Chen and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Observation of the hippocampal damage via MRI and HE staining. Panels (A,B) show the results of T2-weighted phase (T2WI) of MRI. (A) Normal group. (B) SE group. (C) AST group. The T2WIs of the hippocampus of the SE group exhibited a higher signal compared to the Normal group. AST treatment showed a lower signal compared to the SE group. Panels (D–F) show the results of HE staining in the hippocampus. (D,d) Normal group. (E,e) SE group. (F,f) AST group. AST treatment improved the morphological changes in SE rats.