Table 3.

Impacts of MALAT1 expression, miR-197-3p expression and clinical characteristics on the survival rates of non-small cell lung cancer patients

Characteristics	Univariate analysis			Multivariate analysis
	Hazard Ratio	95% CI	P value	Hazard Ratio	95% CI	P value
LncRNA MALAT1 expression
High vs. Low	5.21	3.09–8.77	<0.001	5.56	2.94–10.00	<0.001
miR-197-3p expression
High vs. Low	3.32	2.02–5.46	<0.001	2.63	1.35–5.00	0.004
Age
>60 vs. ≤60	1.10	0.67–1.80	0.699	1.27	0.72–2.25	0.415
Gender
Female vs. Male	0.96	0.57–1.62	0.885	0.82	0.44–1.54	0.533
Smoking
Yes vs. No	1.71	1.05–2.77	0.030	2.15	1.18–3.93	0.013
Tumor size
>3 cm vs. ≤3 cm	2.95	1.69–5.12	<0.001	2.02	1.05–3.90	0.036
Histology grade
Poorly and unknown vs. Well and moderate	3.92	1.86–8.23	<0.001	2.53	1.14–5.62	0.023
Histological type
Adenocarcinoma vs. Others	0.82	0.48–1.41	0.473	0.69	0.36–1.29	0.241
Squamous cell carcinoma vs. Others	0.96	0.45–2.01	0.904	0.68	0.29–1.63	0.390
TNM stage
III–IV vs. I–II	1.95	1.18–3.20	0.009	0.83	0.42–1.63	0.581
Lymph node metastasis
Yes vs. No	1.20	0.73–1.97	0.467	1.00	0.55–1.81	0.989