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The synergistic anti-leukemic effects of HHT + IPI504 in FLT3-ITD (+) AML samples.
(A -E) The FLT3-ITD (+) primary AML cells were treated with HHT, IPI504 and HHT+IPI504 for 48 h then cell viability was measured by MTT assay. And the CI values were calculated by Calcusyn. The (B), (D) and (E) are relapsed/refractory AML samples.
