Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 5;16:72. doi: 10.1186/s12974-019-1460-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 4 — Overexpression of N-glycosylation defective CD147 mutant N152Q blocked MMPs production in BMECs. a Representative Western blots of CD147, caveolin-1, occludin, and ZO-1. b, c Densitometric quantification results of CD147 and caveolin-1 in control and empty vector- or N152Q mutant-transfected BMECs. d, e MMP-2/9 activity in the conditioned media. f, g Densitometric quantification results of occludin and ZO-1. Data expressed as mean ± SEM and analyzed by one-way ANOVA. Asterisk (*) denotes comparison with the control group and pound (#) with the empty vector group. One asterisk (*) represents P < 0.05, two (**) P < 0.01, and three (***) P < 0.001. EV empty vector, BMEC brain microvascular endothelial cell, MMP matrix metalloproteinase, ZO-1 zonula occludens-1