Skip to main content
. 2019 Apr 4;19:28. doi: 10.1186/s12880-019-0328-2

Table 3.

Diagnostic Performance of US Characteristics for the Prediction of Malignancy in Thyroid Nodules with Echogenic Foci alone and TIRADS alone

Total Benign Malignant Diagnostic Performance
Sensitivity Specificity Accuracy PPV NPV
Echogenic Foci Type 1 207 54 153 60.2 60.3 60.3 73.9 44.8
Type 2 54 12 42 27.5 77.8 40.6 77.8 27.5
Type 3 94 41 53 20.9 69.9 37.9 56.4 32.1
Type 4 27 16 11 4.3 88.2 33.6 40.7 33.1
Type 5 21 14 7 2.8 89.7 33.1 33.3 33.1
Type 6 41 11 30 11.8 91.9 39.7 73.2 35.8
TIRADS Web-based TIRADS(≥ 8) 199 21 178 70.1 84.6 75.1 89.4 60.2
K-TIRADS High Suspicion 226 28 198 78.0 79.4 78.5 87.6 65.9
ATA guidelines High Suspicion 235 30 205 96.2 56.5 86.5 87.2 83.0
Russ et al. (≥ 4B) 278 61 217 85.4 55.1 74.9 78.1 67.0

TIRADS thyroid image reporting and data system, ATA american thyroid association, PPV positive predictive value, NPV negative predictive value

Type 1 = Punctate echogenic foci (≤ 1 mm) with or without posterior shadowing

Type 2 = Punctate echogenic foci with comet-tail artifact

Type 3 = Large echogenic foci (> 1 mm) without shadowing

Type 4 = Macrocalcification (defined as large echogenic foci (> 1 mm) with shadowing)

Type 5 = Peripheral curvilinear or eggshell echogenic foci with or without shadowing

Type 6 = Nodules with more than one type of echogenic foci