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. 2019 Apr 4;19:28. doi: 10.1186/s12880-019-0328-2

Table 6.

Comparison of Positive Predictive Value in Thyroid Nodules with Echogenic foci Types with different TIRADS Category Combination

Echogenic foci TIRADS PPV TIRADS PPV P value
Type 1 Web-based TIRADS (≥ 8) 90.5 Web-based TIRADS (<  8) 32.2 < 0.001
K-TIRADS High Suspicion 87.8 K-TIRADSa 31.4 < 0.001
ATA High Suspicion 87.1 ATAa 20.0 < 0.001
Russ et al. (≥ 4B) 78.3 Russ et al. (< 4B) 27.8 < 0.001
Type 2 Web-based TIRADS (≥ 8) 91.9 Web-based TIRADS (<  8) 47.1 < 0.001
K-TIRADS High Suspicion 85.0 K-TIRADSa 57.1 0.579
ATA High Suspicion 84.8 ATAa 33.3 0.083
Russ et al. (≥ 4B) 83.0 Russ et al. (<4B) 42.9 0.036
Type 3 Web-based TIRADS (≥ 8) 90.9 Web-based TIRADS (< 8) 45.8 < 0.001
K-TIRADS High Suspicion 83.8 K-TIRADSa 38.6 < 0.001
ATA High Suspicion 84.2 ATAa 10.5 < 0.001
Russ et al. (≥ 4B) 73.5 Russ et al. (<4B) 37.8 < 0.001
Type 4 Web-based TIRADS (≥ 8) 50.0 Web-based TIRADS (<  8) 40.0 > 0.999
K-TIRADS High Suspicion 75.0 K-TIRADSa 34.8 0.237
ATA High Suspicion 75.0 ATAa 16.7 0.191
Russ et al. (≥ 4B) 66.7 Russ et al. (<4B) 33.3 0.187
Type 5 Web-based TIRADS (≥ 8) 66.7 Web-based TIRADS (< 8) 20.0 0.120
K-TIRADS High Suspicion 80.0 K-TIRADSa 18.8 0.025
ATA High Suspicion 80.0 ATAa 16.7 0.080
Russ et al. (≥ 4B) 66.7 Russ et al. (<4B) 20.0 0.120
Type 6 Web-based TIRADS (≥ 8) 90.5 Web-based TIRADS (<  8) 55.0 0.015
K-TIRADS High Suspicion 95.8 K-TIRADSa 41.2 < 0.001
ATA High Suspicion 96.0 ATAa 33.3 < 0.001
Russ et al. (≥ 4B) 89.3 Russ et al. (< 4B) 38.5 < 0.001

TIRADS thyroid image reporting and data system, ATA american thyroid association, PPV positive predictive value

aOther than High suspicion category

TIRADS Thyroid image reporting and data system, ATA American Thyroid Association, PPV Positive Predictive Value

Type 1 = Punctate echogenic foci (≤ 1 mm) with or without posterior shadowing

Type 2 = Punctate echogenic foci with comet-tail artifact

Type 3 = Large echogenic foci (> 1 mm) without shadowing

Type 4 = Macrocalcification (defined as large echogenic foci (> 1 mm) with shadowing

Type 5 = Peripheral curvilinear or eggshell echogenic foci with or without shadowing

Type 6 = Nodules with more than one type of echogenic foci