Fig. 4.

VP1 IBs cytotoxicity assay and tolerance of mice to oral VP1 IBs administration. a Cultured HeLa cell growth in absence and in presence of increasing amounts of VP1 IBs added to the culture media. b Body weight of animals during oral administration of VP1 IBs compared with control mice. c Food intake (per day and accumulated values) of mice during oral administration of VP1 IBs compared with control mice. d Histological sections of the intestine of VP1 IBs oral administered mice and control mice