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. 2019 Apr 4;18:66. doi: 10.1186/s12934-019-1115-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — CVB3-specific immune responses induced by oral administration of VP1 IBs. a CVB3-specific fecal IgA level. b CVB3-specific serum IgG level. c Frequency of IFN-ɣ producing cells in MLN. **P < 0.01; ***P < 0.001