Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 21;12(4):801–815. doi: 10.1016/j.stemcr.2019.02.007

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Comparative Mature Cell Accumulation and Kinetics by Transplanted Hematopoietic Stem and Progenitor Cell Populations

The total numbers of RBCs (A), platelets (B), GMs (C), B cells (D), and T cells (E) present per mouse per transplanted HSPC. (A′–E′) The approximate time points and cell numbers for peak donor-derived mature cells from (A–E), respectively.

Data were generated from the transplantation and cell distribution experiments of Figure 1. The mature cell production capacity was always in the same order: HSCs > MPP^F > CLP^F (for B and T cells) and HSCs > MPP^F > CMP > CMP^F > MEP > GMP (for RBCs, platelets, and GMs). The only exception was that significantly more GMs accumulated after CMP^F than after CMP transplantation (C and C′; p < 0.0009 by Student's two-tailed t test). All other comparisons were also significant. See also Figure S3.