Table 3.

Comparison of gene and protein expression of HSL and ATGL between obese and lean subjects in previous studies

Study, year [reference no.]	BMI, kg/m2		Number of subjects males/females	Hormone-sensitive lipase (HSL)		Adipose triglyceride lipase (ATGL)		Lipolysis
	obese	lean		mRNA expression	protein content	mRNA expression	protein content
Visceral adipose tissue
2006 [17]	42	24	32/61	↑		↔
2007 [18]	32	25	06/10			↑	↔	↔
2008 [19]	33	24	46/39	↓		↔
2009 [20]*	24	23	00/20		↓		↔
2009 [21]	42	23	00/16	↑	↓
Subcutaneous adipose tissue
1999 [22]	34	23	29/19	↓	↓			↓
2006 [17]	39	24	00/96	↓		↔
2007 [23]**	36	32	16/28	↓	↓	↓	↓
2007 [24]*	42	23	00/47		↓		↔	↓
2007 [18]	32	25	06/10			↑	↑	↓
2008 [19]	33	24	46/39	↓		↓
2009 [21]	42	23	00/16	↑	↓

PCO = Poly cystic ovarian syndrome.

↓ Decrease versus obese.

↑ Increase versus obese.

↔ no difference.

^*Comparison between obese / PCO and lean subjects.

^**Comparison between (clamp measured) insulin-resistant versus insulin-sensitive subjects.