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. 2019 Mar 29;10:311. doi: 10.3389/fphar.2019.00311

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Copyright © 2019 Pigat, Reyes-Gomez, Boutillon, Palea, Barry Delongchamps, Koch and Goffin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prostate inflammatory status. (A) Representative illustrations of CD45 immunostaining of half prostate sections from the various groups (only the highest dose is shown for WS^® 1541). CD45-positive cell foci are circled in black, and one typical foci is shown at high magnification. The number of CD45-positive cell clusters was quantified for half prostate (B) and for each individual lobe (C) by image analysis as described in the section “Materials and Methods.” The results are normalized to the vehicle condition (see Table 1C for averaged crude values). Symbol: ^∗ vs. vehicle group, ANOVA, followed by Tukey’s. D, dorsal prostate; L, lateral prostate; V, ventral prostate; U, urethra.