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. 2019 Mar 29;10:311. doi: 10.3389/fphar.2019.00311

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Copyright © 2019 Pigat, Reyes-Gomez, Boutillon, Palea, Barry Delongchamps, Koch and Goffin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential regulation of pro-inflammatory cytokines/chemokines by WS^® 1541. Typical examples of gene regulation by WS^® 1541: genes that are (i) significantly downregulated in all lobes and at all doses (IL-15), (ii) significantly downregulated in all lobes but not at all doses (CCL2), (iii) significantly downregulated in some but not all lobes (CCL8), (iv) unaltered (CXCL10), and (v) regulated in opposite ways in different lobes (CD40lg). See text for the section “Discussion.” Statistical analysis was performed by ANOVA, followed by Tukey’s.