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ZIKV infection causes dermatological manifestations in adult tree shrews. (A) Study design and experimental parameters. Twenty-six tree shrews were inoculated via the s.c. route with 106 PFU of ZIKV strain GZ01. The yellow box indicates the time course for clinical observations and virological assays. (B) Representative images of dermatological manifestations in ZIKV-inoculated tree shrews. Heat-inactivated ZIKV and PBS were used as the controls. Red arrows denote the injection sites.
