Figure 6.
JMT up-regulated the IGF-1, p-IGF-1R, P0, and PMP22 protein expression in the sciatic nerve of the DPN rats. (A) The IGF-1, p-IGF-1R, P0, and PMP22 protein expression level measured by Western blot analysis, normalized to β-actin in Con, DM, JMT-L, JMT-M, JMT-H, NTP groups, respectively. (B) Relative optical density of IGF-1 expression in different groups. (C) Relative optical density of p-IGF-1R expression in different groups. (D) Relative optical density of P0 expression in different groups. (E) Relative optical density of PMP22 expression in different groups. **P < 0.01 vs. Con group; ▴P < 0.05 vs. DM group, ▴▴P < 0.01 vs. DM group; ▾P < 0.05 vs. JMT-M group, ▾▾P < 0.01 vs. JMT-M group; □P < 0.05 vs. JMT-L group, □□P < 0.01 vs. JMT-L group; °P < 0.05 vs. NTP group, °°P < 0.01 vs. NTP group.