Figure 2.

Paw withdrawal threshold (PWT) (mean ± standard deviation) for A) right-hind paw (RHP) and B) left-hind paw (LHP) by day (D). Time is distributed differently for the surgical groups (D −1, D14, D28, and D42) and the MIA group (D −1, D3, D7, D14, and D21). *a day when there is a statistically significant decreased value compared to its baseline (see Table II for details). CCLT — cranial cruciate ligament transection; DMM — destabilization of medial meniscus; COMBO — combination of CCLT and DMM models; MIA — intra-articular injection of monosodium iodoacetate.