Figure 4.

Amino acid substitutions in neutralizing epitopes in NB1 and 18 field Korean strains. Amino acid position was numbered based on NB1 epitopes COE (aa 501–640) and S1D (aa 638–791). Unique amino acids in NB1 are indicated with empty arrows, while those with physical property changes (polar to non-polar or vice versa) are indicated with filled arrows. Shaded areas in COE and S1D are regions where antigenic indexes (inserted panels) were different due to amino acid variations between NB1 and the other Korean PEDV.