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. 2019 Apr 2;13:1033–1047. doi: 10.2147/DDDT.S186759

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© 2019 Freyer et al. This work is published and licensed by Dove Medical Press Limited

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Glucose and nitrogen metabolism in primary human hepatocytes.

Notes: Cells were cultured in perfused 3-D bioreactors (left column) or static 2-D cultures (right column) without (black circles) or with remimazolam (Rem) application (blue squares). (A, B) Glucose production; (C, D) lactate production; (E, F) urea production; (G, H) ammonia release; n=3, means ± SD. Underlying data can be found online at http://doi.org/10.5281/zenodo.1493510 (files Clinical_chemistry_3D_bioreactors and Clinical_chemistry_2D_cultures).

Glucose and nitrogen metabolism in primary human hepatocytes.

Notes: Cells were cultured in perfused 3-D bioreactors (left column) or static 2-D cultures (right column) without (black circles) or with remimazolam (Rem) application (blue squares). (A, B) Glucose production; (C, D) lactate production; (E, F) urea production; (G, H) ammonia release; n=3, means ± SD. Underlying data can be found online at http://doi.org/10.5281/zenodo.1493510 (files Clinical_chemistry_3D_bioreactors and Clinical_chemistry_2D_cultures).