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. 2019 Mar 29;10:330. doi: 10.3389/fphys.2019.00330

FIGURE 4.

FIGURE 4

Bicuculline microinfusion into the rostral sub-regions in the EPM induces anxiogenic effects. (A) Percentage of time spent in the open arms when vehicle (white bars, n = 5) or BMI (black bars, n = 6) was microinjected into raIC; (B) Percentage of time spent in the open arms when vehicle (white bars, n = 5) or BMI (black bars, n = 6) was microinjected into gIC. Total transitions during the EPM evaluation for the same rats microinjected into pIC (C) or cIC (D). Columns represent the mean ± SEM. ∗p < 0.05 and ∗∗p < 0.01.