Table 3.
Univariable and multivariable logistic regression analyses of the associations of heparinization and other baseline characteristics with the probability of sICH and poor outcome following mechanical thrombectomy in patients with emergent large vessel occlusion.
Variable | sICH | Poor outcome | ||||||
---|---|---|---|---|---|---|---|---|
Univariable logistic regression analysis | Multivariable logistic regression analysis | Univariable logistic regression analysis | Multivariable logistic regression analysis | |||||
Odds ratio (95% CI) |
P-value |
Odds ratio (95% CI) |
P-value |
Odds ratio (95% CI) |
P-value |
Odds ratio (95% CI) |
P-value | |
Age | 1.0 (0.98–1.03) | 0.88 | – | – | 1.04 (1.03–1.06) | <0.01 | 1.04 (1.03–1.06) | <0.01 |
Bridging IVT | 1.23 (0.64–2.36) | 0.54 | – | – | 0.53 (0.37–0.75) | <0.01 | 0.57 (0.39–0.82) | <0.01 |
Admission NIHSS | 1.03 (0.98–1.07) | 0.29 | – | – | 1.12 (1.08–1.15) | <0.01 | 1.11 (1.07–1.14) | <0.01 |
VASCULAR RISK FACTORS | ||||||||
Hypertension | 0.66 (0.35–1.22) | 0.19 | – | – | 1.31 (0.95–1.80) | 0.10 | 1.08 (0.76–1.54) | 0.68 |
Moderate to heavy alcohol consumption | 0.59 (0.30–1.15) | 0.12 | – | – | 0.71 (0.52–0.99) | 0.04 | 0.69 (0.48–0.99) | 0.04 |
Cardio-embolism stroke | 1.83 (0.89–3.77) | 0.10 | 1.89 (1.05–3.96) | 0.04 | 0.92 (0.62–1.35) | 0.66 | – | – |
Posterior circulation stroke | 0.31 (0.11–0.88) | 0.03 | 0.33 (0.11–0.98) | 0.05 | 1.87 (1.27–2.76) | <0.01 | 1.84 (1.20–2.83) | <0.01 |
Heparinization | 1.89 (1.01–3.54) | 0.04 | 2.36 (1.19–4.67) | 0.01 | 1.41 (1.02–1.95) | 0.03 | 1.79 (1.23–2.59) | <0.01 |
sICH, symptomatic intracranial hemorrhage; CI, confidence interval; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale.