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. 2019 Mar 29;10:299. doi: 10.3389/fneur.2019.00299

Table 3.

Univariable and multivariable logistic regression analyses of the associations of heparinization and other baseline characteristics with the probability of sICH and poor outcome following mechanical thrombectomy in patients with emergent large vessel occlusion.

Variable sICH Poor outcome
Univariable logistic regression analysis Multivariable logistic regression analysis Univariable logistic regression analysis Multivariable logistic regression analysis
Odds ratio
(95% CI)
P-value Odds ratio
(95% CI)
P-value Odds ratio
(95% CI)
P-value Odds ratio
(95% CI)
P-value
Age 1.0 (0.98–1.03) 0.88 1.04 (1.03–1.06) <0.01 1.04 (1.03–1.06) <0.01
Bridging IVT 1.23 (0.64–2.36) 0.54 0.53 (0.37–0.75) <0.01 0.57 (0.39–0.82) <0.01
Admission NIHSS 1.03 (0.98–1.07) 0.29 1.12 (1.08–1.15) <0.01 1.11 (1.07–1.14) <0.01
VASCULAR RISK FACTORS
Hypertension 0.66 (0.35–1.22) 0.19 1.31 (0.95–1.80) 0.10 1.08 (0.76–1.54) 0.68
Moderate to heavy alcohol consumption 0.59 (0.30–1.15) 0.12 0.71 (0.52–0.99) 0.04 0.69 (0.48–0.99) 0.04
Cardio-embolism stroke 1.83 (0.89–3.77) 0.10 1.89 (1.05–3.96) 0.04 0.92 (0.62–1.35) 0.66
Posterior circulation stroke 0.31 (0.11–0.88) 0.03 0.33 (0.11–0.98) 0.05 1.87 (1.27–2.76) <0.01 1.84 (1.20–2.83) <0.01
Heparinization 1.89 (1.01–3.54) 0.04 2.36 (1.19–4.67) 0.01 1.41 (1.02–1.95) 0.03 1.79 (1.23–2.59) <0.01

sICH, symptomatic intracranial hemorrhage; CI, confidence interval; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale.