Number of pleurodesis methods evaluated	Number of trials included in network	Tau2 (95% CI)	Global inconsistency identified?	Loop‐specific inconsistency identified? If so, loop showing inconsistency with ROR (95% CI)
Whole network	16	41	0.88 (0.42, 1.482)	No	Yes TS‐TP‐BL 7.0 (1.1, 43.8) TS‐BL‐ME 10.2 (1.1, 96.9)
Only data collected at 1 month	13	24	0.80 (0.14, 1.66)	No	Yes BL‐MX‐ME 54.2 (2.0, 1469.5)
Only data collected at 3 months	9	10	0.55 (0.02, 1.84)	No	No
Only data collected at 6 months	7	10	1.09 (0.09, 1.95)	No	Yes TS‐TP‐BL 11.7 (1.1, 123.3)
Trials excluding patients with trapped lung	9	13	0.71 (0.04, 1.85)	No	No
Trials using a clinico‐radiological definition of pleurodesis	16	29	1.16 (0.59, 1.87)	No	Yes TS‐BL‐ME 12.9 (1.3, 126.3) TS‐TP‐BL 11.6 (1.02, 132.5)
Trials using large‐bore chest tubes	9	16	1.32 (0.51, 1.95)	No	Yes TS‐BL‐TC 15.2 (1.5, 151.4) TS‐BL‐ME (12.2 (1.2, 121.2)
Trials with a lower risk of bias (high risk of bias for < 2 domains)	16	36	0.46 (0.03, 1.09)	No	Yes TS‐BL‐ME 12.2 (1.2, 125.3) TS‐TP‐BL 8.5 (1.2, 60.3)
BL = Bleomycin; CP = C. parvum; DX = Doxycycline; IO = Iodine; ME = Mepacrine; MU = Mustine; MX = Mitoxantrone; PL = Placebo; TC = Tetracycline; TP = Talc poudrage; TS = Talc slurry