Talc slurry	Talc poudrage	Bleomycin	Tetracycline	C. parvum	Interferon	Iodine	Indwelling pleural catheter	Placebo	Mustine	Mitoxantrone	Mepacrine	Doxycycline	Triehylenethiophosphoramide	Adriamycin
Talc poudrage	0.60 (0.23, 1.18)	NA	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐
Bleomycin	2.48 (1.11, 5.62)	4.20 (1.86, 11.54)	NA	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐
Tetracycline	3.31 (1.30, 8.09)	5.61 (2.26, 15.98)	1.33 (0.65, 2.62)	NA	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐
C. parvum	0.38 (0.08, 1.63)	0.64 (0.14, 3.10)	0.15 (0.04, 0.55)	0.11 (0.03, 0.43)	NA	‐	‐	‐	‐	‐	‐	‐	‐	‐	‐
Interferon	8.29 (1.71, 41.07)	13.94 (3.07, 81.87)	3.34 (0.85, 13.22)	2.51 (0.56, 12.10)	22.05 (3.30, 153.40)	NA	‐	‐	‐	‐	‐	‐	‐	‐	‐
Iodine	1.48 (0.35, 5.83)	2.52 (0.65, 10.61)	0.60 (0.15, 2.26)	0.45 (0.10, 1.93)	3.95 (0.59, 25.86)	0.18 (0.02, 1.16)	NA	‐	‐	‐	‐	‐	‐	‐	‐
Indwelling pleural catheter	3.47 (1.17, 10.63)	5.81 (1.70, 26.41)	1.39 (0.36, 5.52)	1.05 (0.26, 4.57)	9.32 (1.49, 60.52)	0.42 (0.06, 2.92)	2.33 (0.41, 14.76)	NA	‐	‐	‐	‐	‐	‐	‐
Placebo	16.07 (4.32, 70.28)	27.28 (7.17, 146.30)	6.51 (1.91, 25.79)	4.89 (1.40, 20.52)	43.17 (7.58, 289.30)	1.94 (0.32, 13.75)	10.87 (1.86, 75.98)	4.63 (0.85, 29.52)	NA	‐	‐	‐	‐	‐	‐
Mustine	5.82 (1.35, 23.26)	9.84 (2.59, 41.00)	2.32 (0.59, 8.80)	1.74 (0.50, 6.25)	15.22 (3.09, 79.85)	0.70 (0.10, 4.48)	3.91 (0.64, 24.53)	1.68 (0.27, 9.52)	0.36 (0.06, 1.95)	NA	‐	‐	‐	‐	‐
Mitoxantrone	10.77 (2.88, 46.75)	18.28 (4.88, 96.33)	4.34 (1.36, 16.02)	3.28 (0.93, 13.77)	28.81 (5.23, 188.00)	1.30 (0.22, 8.91)	7.21 (1.31, 50.05)	3.12 (0.56, 19.44)	0.67 (0.20, 2.21)	1.88 (0.35, 12.09)	NA	‐	‐	‐	‐
Mepacrine	1.02 (0.31, 3.08)	1.74 (0.50, 6.54)	0.41 (0.12, 1.23)	0.31 (0.09, 1.01)	2.72 (0.49, 14.88)	0.12 (0.02, 0.69)	0.69 (0.13, 3.72)	0.29 (0.06, 1.37)	0.06 (0.01, 0.25)	0.18 (0.03, 0.90)	0.10 (0.02, 0.38)	NA	‐	‐	‐
Doxycycline	0.75 (0.06, 8.34)	1.30 (0.11, 14.97)	0.30 (0.03, 3.13)	0.23 (0.02, 2.49)	1.98 (0.24, 16.02)	0.09 (0.01, 1.36)	0.51 (0.03, 7.34)	0.22 (0.01, 2.90)	0.05 (0.00, 0.61)	0.13 (0.01, 1.70)	0.07 (0.00, 0.96)	0.73 (0.05, 9.59)	NA	‐	‐
Triethylenethiophosphoramide	5.34 (0.65, 47.58)	9.11 (1.09, 92.17)	2.14 (0.27, 18.82)	1.62 (0.20, 14.58)	14.32 (1.27, 182.00)	0.64 (0.05, 8.18)	3.60 (0.33, 44.88)	1.53 (0.15, 17.84)	0.33 (0.04, 2.79)	0.92 (0.08, 11.35)	0.49 (0.05, 4.67)	5.21 (0.83, 38.34)	7.11 (0.33, 182.30)	NA	‐
Adriamycin	2.07 (0.04, 104.50)	3.56 (0.06, 181.20)	0.84 (0.01, 40.14)	0.63 (0.01, 30.57)	5.54 (0.09, 290.10)	0.25 (0.00, 14.49)	1.40 (0.02, 78.69)	0.60 (0.01, 33.16)	0.13 (0.00, 6.70)	0.36 (0.01, 17.48)	0.19 (0.00, 10.55)	2.06 (0.03, 109.70)	2.85 (0.03, 224.70)	0.39 (0.00, 28.73)	NA
Viscum	0.36 (0.02, 4.78)	0.62 (0.03, 9.01)	0.15 (0.01, 1.70)	0.11 (0.01, 1.43)	0.96 (0.05, 16.17)	0.04 (0.00, 0.74)	0.24 (0.01, 4.26)	0.10 (0.00, 1.72)	0.02 (0.00, 0.34)	0.06 (0.00, 1.06)	0.03 (0.00, 0.49)	0.35 (0.02, 5.51)	0.48 (0.01, 15.59)	0.07 (0.00, 1.81)	0.17 (0.00, 18.96)
Results that are statistically significant at the conventional level of P < 0.05 are shaded in grey. ‐ indicates the odds ratio is already expressed elsewhere in the table comparing the interventions the other way around. NA= not applicable.