Treatment	Talc slurry	Talc poudrage	Bleomycin	Tetracycline	C. parvum	Placebo	Mepacrine
Talc poudrage	0.47 (0.23, 0.96); n = 1	NA	‐	‐	‐	‐	‐
Bleomycin	1.66 (0.41, 6.80) Tau2 = 0; I2 = 0%; n = 2*	0.28 (0.01, 7.31); n = 1	NA	‐	‐	‐	‐
Tetracycline	3.28 (0.73, 14.68); n = 1	NA	1.65 (0.79, 3.43); Tau2 = 0.19; I2 = 34%; n = 4*	NA	‐	‐	‐
C. parvum	NA	NA	1.42 (0.54, 3.75); Tau2 = 0; I2 = 0%; n = 2	2.44 (0.69, 8.66); n = 1	NA	‐	‐
Interferon	NA	NA	0.03 (0.00, 0.53); n = 1	NA	NA	NA	NA
Iodine	NA	0.10 (0.01, 1.99); n = 1	NA	NA	NA	NA	NA
Indwelling pleural catheter	3.22 (0.13, 82.38); n = 1	NA	NA	NA	NA	NA	NA
Placebo	NA	NA	NA	NA	NA	NA	‐
Mustine	NA	NA	NA	0.03 (0.00, 0.56); n = 1	NA	NA	NA
Mitoxantrone	NA	NA	2.08 (0.64, 6.76); n = 1	NA	NA	NA	NA
Mepacrine	NA	NA	2.15 (0.52, 9.00); n = 1	5.60 (0.81, 38.51); n = 1	NA	14.53 (0.71, 298.21); n = 1*	NA
Doxycycline	NA	NA	1.19 (0.37, 3.80); Tau2 = 0.30; I2 = 42%; n = 2	NA	0.10 (0.01, 0.96); n = 1	NA	NA
Triethylenethiophosphoramide	NA	NA	NA	NA	NA	7.43 (0.35, 156.28); n = 1*	0.48 (0.10, 2.30); n = 1*
n = the number of studies included in the pair‐wise comparison. * indicates that the comparison included a three‐arm study. NA = no direct pair‐wise comparison available. Results that are statistically significant at the conventional level of P < 0.05 are shaded in grey. ‐ indicates the odds ratio is already expressed elsewhere in the table comparing the interventions the other way around