Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Biophysical properties of R1193Q SCN5A channel.
| Steady-state activation |
Steady-state inactivation |
Recovery from inactivation |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| V1/2,mV | k,mV | n | V1/2,mV | k,mV | n | Tfast, ms(%) | Tslow, ms(%) | n | |
| WT | -26.4 ± 0.4 | 6.7 ± 0.4 | 6 | -63.4 ± 0.9 | 4.9 ± 0.1 | 7 | 9.6(87) | 48.3(13) | 9 |
| R1193Q | -25.2 ± 0.2 | 7.6 ± 0.2 | 7 | -62.8 ± 1.7 | 4.8 ± 0.2 | 8 | 9.7(81) | 40.6(19) | 10 |
Because the functions for recovery from inactivation were fitted to the averaged data, error estimates on these parameters were not obtained.
