Table 1. Patient Characteristics.
| Characteristic | Level of Impairment | |
|---|---|---|
| Mild Cognitive Impairment (n = 6905) | Dementia (n = 4504) | |
| Age, median (IQR), y | 75 (70-79) | 77 (72-81) |
| Sex, No. (%) | ||
| Women | 3425 (49.6) | 2379 (52.8) |
| Men | 3480 (50.4) | 2125 (47.2) |
| Race, No. (%)a | ||
| Black or African American | 206 (3.0) | 225 (5.0) |
| White | 6212 (90.0) | 3828 (85.0) |
| Other race | 487 (7.1) | 451 (10.0) |
| Hispanic ethnicity, No. (%)b | 209 (3.0) | 244 (5.4) |
| Highest level of education, No. (%) | ||
| High school graduate (including equivalency) or less | 1824 (26.4) | 1917 (42.6) |
| Some college or associate degree | 1763 (25.5) | 933 (20.7) |
| Bachelor’s degree | 1777 (25.7) | 927 (20.6) |
| Postgraduate degree | 1541 (22.3) | 727 (16.1) |
| MMSE, median (IQR)c | 27 (25-29) | 22 (18-25) |
| MoCA, median (IQR)c | 23 (21-25) | 18 (14-21) |
| Alzheimer disease leading suspected pre-PET etiology, No. (%) | 5043 (73.0) | 3727 (82.7) |
| Taking Alzheimer disease drugs at enrollment, No. (%) | 2384 (34.5) | 2671 (59.3) |
| Amyloid PET results, No. (%)d | ||
| Positive | 3817 (55.3) | 3154 (70.1) |
| Negative | 3082 (44.7) | 1347 (29.9) |
Abbreviations: IQR, interquartile range; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; PET, positron emission tomography.
a
Race as recorded by dementia specialist, study coordinator, or practice administrator. “Other race” indicates American Indian, Asian, Native Hawaiian or Pacific Islander, unknown, or not reported.
b
Ethnicity as recorded by dementia specialist, study coordinator, or practice administrator; grouped as Hispanic and other (not Hispanic, unknown, or not reported).
c
Range, 0-30; lower scores indicate worse global cognition.
d
Nine cases with uninterpretable test results not included (6 in MCI group, 3 in dementia group).