Table 1. Maternal and Neonatal Characteristics of Neonates Aged 22 to 28 Weeks of Gestation.
| Characteristic | No. (%) | ||
|---|---|---|---|
| DCC (n = 1852) | ICC (n = 2828) | P Valuea | |
| Maternal Characteristics | |||
| Hypertension | 292 (15.9) | 439 (15.7) | .88 |
| Antenatal steroid use | 1768 (95.9) | 2572 (91.9) | <.001 |
| Cesarean delivery | 984 (53.2) | 1737 (61.5) | <.001 |
| Neonatal Characteristics | |||
| Male | 974 (52.7) | 1540 (54.5) | .24 |
| GA, median (IQR), wk | 27 (25-28) | 26 (25-27) | <.001 |
| GA group, wk | |||
| <24 | 72 (3.9) | 215 (7.6) | <.001 |
| 24 | 190 (10.3) | 391 (13.8) | |
| 25 | 271 (14.6) | 475 (16.8) | |
| 26 | 376 (20.3) | 525 (18.6) | |
| 27 | 410 (22.1) | 590 (20.9) | |
| 28 | 533 (28.8) | 632 (22.4) | |
| Birth weight, median (IQR), g | 930 (760-1120) | 870 (700-1060) | <.001 |
| Birth weight group, g | |||
| ≤1000 | 1113 (60.1) | 1943 (68.7) | <.001 |
| >1000 | 739 (39.9) | 885 (31.3) | |
| Apgar score <7 at 5 min | 670 (36.3) | 1323 (46.9) | <.001 |
| SNAP-II score, median (IQR) | 14 (5-21) | 14 (9-24) | <.001 |
| Small for gestational age | 152 (8.2) | 272 (9.6) | .10 |
| Need for ventilation by endotracheal tube at birth | 805 (43.5) | 1526 (54.0) | <.001 |
| Extensive cardiopulmonary resuscitation (chest compression for >30 s, with or without epinephrine) | 69 (3.7) | 197 (7.0) | <.001 |
| Respiratory distress syndrome | 1538 (84.7) | 2424 (88.7) | <.001 |
| Surfactant administration | 1249 (67.4) | 2075 (73.4) | <.001 |
| Patent ductus arteriosus | 922 (50.5) | 1664 (60.6) | <.001 |
Abbreviations: DCC, deferred cord clamping; GA, gestational age; ICC, immediate cord clamping; IQR, interquartile range; SNAP-II, Score for Neonatal Acute Physiology II.
a
Significance was assessed using a Wilcoxon rank sum test for continuous variables and Pearson χ2 test for categorical variables.