Table 1.
Multicolor Flow Cytometry Reveals a Decrease in SVZ Neural Stem Cells after Igf2 Conditional Deletion
| Cell Type | NSC | MP1 | MP2 | GRP/MP3 | MP4 | PFMP | BNAP | GRP3 |
|---|---|---|---|---|---|---|---|---|
| WT | 1.27% ± 0.09%a | 18.73% ± 2.53% | 4.30% ± 1.30% | 10.33% ± 1.40% | 0.50% ± 0.31% | 0.90% ± 0.23% | 8.68% ± 1.90% | 0.34% ± 0.07% |
| iKO | 1.01% ± 0.07%∗b | 21.87% ± 2.02% | 4.91% ± 1.46% | 8.33% ± 1.30% | 0.33% ± 0.21% | 1.03% ± 0.19% | 13.46% ± 2.30% | 0.38% ± 0.06% |
See also Figure S3. NSC, neural stem cell; MP1, multipotential 1; MP2, multipotential 2; MP3/GRP2, multipotential 3/glial restricted progenitor 2; PFMP, PDGF- and FGF-responsive multipotential progenitors; BNAP/GRP1, bipotential neuronal-astrocytic precursor/glial restricted progenitor 1; GRP3, glial restricted progenitor 3; WT, wild-type; iKO, inducible KO.
a
Data are presented as mean values ± SEM, n = 17 WT and 19 iKO mice of both sexes.
b
∗p < 0.05 by one-way ANOVA and Tukey's post hoc test.