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IMD upregulated the Wnt/β-catenin signaling pathway. (A) Western blot of β-catenin, p-β-catenin (Ser675), GSK3β, GSK3β (Ser9), β-actin expression from each group. (B,C) Histogram shows the relative level of proteins, IWR-1-endo can specifically inhibit the level of β-catenin without changing the GSK3β expression. Results are expressed as the mean ± SD (n = 8, *p < .01 vs. control, #p < .01 vs. H/R group, &p < .05 vs. H/R + IMD group).
