Table 2.

Minimum inhibitory concentration – MIC (in μg/mL) and minimum bactericidal concentration – MBC (in μg/mL) of thiazolin-4-one derivatives ^a .

Samples	S. aureus ATCC 49444			E. coli ATCC 25922
	MIC	MBC	MBC/MIC ratio	MIC	MBC	MBC/MIC ratio
2	62.5	62.5	1	62.5	125	2
5	62.5	125	2	62.5	125	2
8	62.5	125	2	15.62	31.25	2
10	62.5	125	2	7.81	15.62	2
11	62.5	125	2	62.5	125	2
3a	31.25	62.5	2	62.5	62.5	1
3b	31.25	62.5	2	62.5	62.5	1
3c	31.25	31.25	1	62.5	62.5	1
3d	62.5	125	2	62.5	62.5	1
3e	15.62	31.25	2	62.5	62.5	1
3f	7.81	15.62	2	31.25	62.5	2
3g	31.25	31.25	1	62.5	125	2
3h	0.97	1.95	2	62.5	125	2
6a	62.5	125	2	62.5	125	2
6b	31.25	62.5	2	62.5	125	2
6c	31.25	62.5	2	62.5	125	2
6d	62.5	62.5	1	62.5	125	2
6e	62.5	125	2	62.5	125	2
9a	3.9	7.81	2	62.5	125	2
9b	0.97	1.95	2	15.62	15.62	1
9c	31.25	62.5	2	62.5	125	2
9d	125	250	2	125	250	2
9e	62.5	62.5	1	62.5	125	2
Indolmycin	0.97	1.95	2	31.25	62.5	2
Moxifloxacin	31.25	62.5	2	1.95	3.9	2
Inoculum control	+++	+++	–	+++	+++	–
Broth control	No growth	No growth	–	No growth	No growth	–

The values obtained for the most active compounds are marked in bold.

– indicates no inhibitory activity; +++ indicates growth in all concentrations.

^aAll determinations were performed in triplicate (n = 3) and the average thereof was the final value.