Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HPV 16 E6 variants
| Structural/functional characteristic |
Polymorphisms |
|---|---|
| Destabilize protein structure | R17K, R17T, R17G, R17I, K41E, I59V |
| Destabilize E6-E6AP-p53 complex | R17G, Q21H, T29S, K41E, I59V, H85Y, Q98R |
| Stabilize E6-E6AP-p53 complex | R17I and Q21D |
| Immunogenic region 1 | E14–I34 |
| Immunogenic region 2 | L45–A68 |
