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. 2019 Mar 31;26(1):393–403. doi: 10.1080/10717544.2019.1587044

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Dermal EB distributed along vasculatures and the perivascular spaces. The EB distribution was observed in the mystacial pad at 2.0 h-post injection and the sections from edge of injection site. (A) and (B) Evans blue diffused into the mystacial sweat glands and hair follicles. (C) EB distributed in the fasciculus and the perineurium. (D) and (E) Evans blue diffused along endothelial cells and perivascular tissues. (F) Evans blue distributed along the lymphatic vessel and blood capillary. (G–L) EB overlaid or surrounded VEGF immuno-reactivity. (M–O) EB located around the Lyve1 immuno-reactivity. White arrows: the sweat gland; green dash line: hair follicle; yellow arrows or dash circle: the sensory nerve fibers and fasciculus; blue arrows or dash circles: vasculatures and perivascular spaces or tissues; white arrowheads: the perineurium. The bar is 50 μm, (A–F) 20×, (G–O) 40×.