Table 2.
Comparisons of erythrocyte membrane fatty acid contents.
| Control (n = 8) | Cyclosporine (n = 8) | Cyclosporine with omega-3 FA (n = 8) | p Value | |
|---|---|---|---|---|
| Saturated | 42.8 ± 0.6 | 40.8 ± 1.4* | 42.8 ± 0.7** | .009 |
| Myristic | 0.27 ± 0.04 | 0.41 ± 0.07* | 0.36 ± 0.10 | .020 |
| Palmitic | 25.1 ± 1.3 | 26.9 ± 1.5* | 29.0 ± 0.4*,** | .001 |
| Stearic | 17.0 ± 1.7 | 13.3 ± 0.9* | 13.3 ± 0.7* | .003 |
| Lignoceric | 0.47 ± 0.05 | 0.24 ± 0.08* | 0.21 ± 0.04* | .001 |
| Monounsaturated | 11.6 ± 0.8 | 14.9 ± 1.1* | 13.5 ± 1.0* | .001 |
| Palmitoleic | 0.41 ± 0.19 | 1.4 ± 0.3* | 1.0 ± 0.5* | .001 |
| Oleic | 10.7 ± 0.6 | 13.1 ± 0.7* | 12.0 ± 0.5*,** | .001 |
| Polyunsaturated | 44.7 ± 0.6 | 43.2 ± 0.8* | 42.7 ± 0.9* | .003 |
| Omega-6 | 38.6 ± 1.6 | 40.7 ± 0.7* | 36.0 ± 1.0*,** | .001 |
| Linoleic | 9.3 ± 0.8 | 11.0 ± 1.1* | 13.2 ± 1.4*,** | .002 |
| AA | 25.9 ± 1.5 | 24.2 ± 1.1* | 19.8 ± 1.2*,** | .001 |
| Omega-3 | 6.2 ± 1.8 | 2.5 ± 0.1* | 6.7 ± 0.8** | .003 |
| Alpha-linolenic | 0.06 ± 0.02 | 0.09 ± 0.05 | 0.10 ± 0.05 | .442 |
| EPA | 0.48 ± 0.30 | 0.09 ± 0.04* | 0.81 ± 0.15** | .001 |
| DHA | 3.6 ± 0.7 | 1.7 ± 0.9* | 3.8 ± 0.5** | .003 |
| Omega-3 index | 4.1 ± 0.9 | 1.8 ± 0.1* | 4.6 ± 0.6** | .002 |
| AA/EPA | 91.7 ± 73.7 | 370.8 ± 270.1* | 25.3 ± 5.0*,** | <.001 |
| Omega-6/omega-3 | 6.9 ± 2.4 | 16.6 ± 0.7* | 5.5 ± 0.7** | .002 |
AA: arachidonic acid; EPA: eicosapentaenoic acid; DHA: docosahexaenoic acid; SCD: stearoyl-CoA desaturase.
Data are expressed as means ± SD.
*p < .05, compared to control group.
**p < .05, compared to cyclosporine group.