Skin temperatures 1 h after warm and cold exposures. Values indicate the mean ± SEM temperature of skin in the ear (A), on the forehead (B), over the forearm (C), and on the calf (D) in controls and patients with FMS. Groups were compared using an unpaired, two-tailed Student’s t-test with a cutoff of P < 0.05 for significance, as indicated by the asterisk.