Table 4.
Changes in factors associate with mortality or MODS
| Predictors of mortality | Predictors of MODS | |||
|---|---|---|---|---|
| p-value | HR (cb) | p-value | HR (cb) | |
| D-dimer | 0.005 | 0.69 (0.54 – 0.90) | ||
| Factor II | 0.007 | 0.99 (.98 – 0.99) | ||
| CD8+IFN-γ+ | 0.03 | 1.07 (1.01 – 1.14) | ||
| GM-CSF | 0.036 | 1.01 (1.00 – 1.03) | ||
| IL-12p70 | 0.0006 | 0.69 (0.55 – 0.85) | ||
| IL-17A | 0.01 | 1.08 (1.02 – 1.15) | ||
| IL-1β | 0.009 | 1.75 (1.15 – 2.66) | ||
| IL-2 | 0.018 | 1.21 (1.03 – 1.42) | ||
| IL-23 | 0.041 | 0.99 (0.98 – 1.00) | ||
| EGF | 0.017 | 1.03 (1.00 – 1.06) | ||
| β2 microglobulin | 0.022 | 1.04 (1.00 – 1.07) | ||
| Cystatin C | 0.001 | 1.16 (1.06 – 1.28) | ||
| EV CD11b | <0.0001 | 0.79 (0.70 – 0.88) | 0.0006 | 0.99 (0.99 – 0.99) |
| EV CD66b | 0.007 | 0.99 (0.99 – 0.99) | ||
HR: hazard ratio, cb: confidence bounds. HRs reflect the change in the hazard that is associated with the following magnitude of change in particular variables:
10 units of change: GM-CSF, IL-23, and EGF
100 units of change: EV CD11b and CD66b
1 million units of change: Cystatin C
10 million units of change: β2 microglobulin