. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Int J Colorectal Dis. 2019 Jan 4;34(3):491–499. doi: 10.1007/s00384-018-03221-x

Table 3.

Odds of perioperative and late complications after 2-stage (versus 3-stage) ileal pouch-anal anastomosis, based on multivariable analysis.^a

Complication	Odds Ratio	P-value	95% Confidence Interval
Any perioperative complication after any stage	0.71	0.45	0.29	1.73
Any anastomotic leak or abdominal sepsis	0.90	0.83	0.33	2.40
Pouchitis	1.53	0.38	0.59	3.93
Fistula or abscess	0.49	0.31	0.12	1.94
Late small bowel obstruction	7.12	0.02	1.39	36.5
Anal stricture	0.46	0.25	0.12	1.71
Pouch failure	1.92	0.59	0.18	21.0

Based on multivariable models of each outcome, adjusting for age-adjusted Charlson Comorbidity Index, use of >40 mg/day of prednisone-equivalent corticoid medication prior to first operation, anti-tumor necrosis factor use, other immunomodulator use, urgent status, surgeon experience, and severe disease in surgical specimen. Models for late complications (pouchitis, fistula or abscess, late small bowel obstruction, anal stricture, and pouch failure) were also adjusted for follow-up time.