Table 1:
Baseline characteristics of cases and controls (mean ± SD, or n, %).
| Any Incident VF | Incident Moderate/Severe VF | |||||
|---|---|---|---|---|---|---|
| Control (n=62) | Case (n=26) | p Value | Control (n=46) | Case (n=20) | p Value | |
| Men | 36 (58) | 13 (50) | - | 27 (59) | 10 (50) | - |
| Women | 26 (42) | 13 (50) | - | 19 (41) | 10 (50) | - |
| Age (Years) | 66.3 (8.4) | 68.1 (9.9) | 0.381 | 66.3 (8.9) | 68.2 (10.4) | 0.451 |
| Height (cm) | 169.8 (9.8) | 167.5 (9.2) | 0.310 | 170.1 (9.9) | 167.5 (9.5) | 0.333 |
| Weight (kg) | 83.3 (16.9) | 83.1 (18.6) | 0.973 | 83.3 (18.2) | 83.4 (20.0) | 0.974 |
| BMI | 28.9 (6.0) | 29.7 (7.0) | 0.612 | 28.8 (6.4) | 29.8 (7.6) | 0.585 |
| Current smoker (yes/no) | 4 (6.5) | 5 (19.2) | 0.117 | 2 (4.3) | 3 (15) | 0.159 |
| Total alcohol intake (oz/wk) | 2.4 (3.3) | 2.0 (3.1) | 0.584 | 2.4 (3.5) | 1.75 (3.4) | 0.511 |
| Prevalent VF, any (yes/no) | 3 (4.8) | 14 (53.9) | < 0.001 | 3 (6.5) | 10 (50) | < 0.001 |
| Prevalent VF, moderate/severe (yes/no) | 1 (1.6) | 3 (11.5) | 0.076 | 1 (2.2) | 2 (10) | 0.216 |
| Vertebral Strength, CT-FEA (N) | 8706 (2914) | 6552 (2391) | 0.001 | 8843 (3178) | 6168 (2076) | < 0.001 |
| L3 Trabecular vBMD (mg/cm3) | 107.3 (35.3) | 86.0 (30.9) | 0.009 | 108.8 (38.8) | 84.9 (29.6) | 0.017 |
| L3 Integral vBMD (mg/cm3) | 200.2 (38.3) | 165.9 (33.8) | < 0.001 | 200.3 (42.1) | 160.9 (30.6) | < 0.001 |
| L3 CT-based aBMD (g/cm2) | 1.08 (0.21) | 0.97 (0.23) | 0.032 | 1.08 (0.21) | 0.92 (0.19) | 0.006 |
| L3 CT-based BMC (g) | 9.16 (2.57) | 7.31 (1.96) | < 0.001 | 9.28 (2.73) | 6.95 (1.74) | < 0.001 |