Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A) Unique variants reported following re-classification, which included downgraded variants. B) Gene-specific adjusted prevalence, which excluded downgraded variants originally disclosed as pathogenic or likely pathogenic. VUS: variant of uncertain significance LP: likely pathogenic P: pathogenic
