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. Author manuscript; available in PMC: 2020 Apr 4.
Published in final edited form as: Cell. 2019 Mar 28;177(2):315–325.e14. doi: 10.1016/j.cell.2019.02.036

Figure 2: The steroid hormone 20E regulates both egg and parasite numbers.

Figure 2:

(A) Injecting wild type females with the ecdysteroid oxidase E22O reduces ecdysteroid levels in the female 26 h pBM compared to BSA-injected controls (Cntrl) (unpaired t-test). (B–C) E22O-injected females (B) produce fewer eggs (Mann-Whitney) and (C) have fewer oocysts at 8 d pIBM (GLM, Poisson distribution). There is no effect on infection prevalence (P) (Chi-Squared). (D) Egg and oocyst numbers are positively correlated in control and E22O-injected females (Spearman’s correlations. Lines show data trends). N = sample size.