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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Xenotransplantation. 2018 Oct 5;26(2):e12465. doi: 10.1111/xen.12465

Figure 2. Cardiac xenograft survivals and histopathological examination;

Figure 2.

(A) Cardiac xenograft survivals of both GTKO.CD46 and GTKO.CD46.hTBM xenograft in recipient baboons. (B) Hematoxylin and eosin staining of biopsy of xenograft expressing GTKO.CD46.hTBM gene (i (20X) & ii (400X)) without any sign of rejection or thrombotic microangiopathy; and, explanted GTKO.CD46 xenograft without hTBM expression (iii, iv & v (20X)) indicating myocardial destruction and widespread fibrin micro-thrombi. (Arrows).